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This paper is a general overview of the Rubella infection which acute febrile disease of a viral cause which mainly occurs in childhood and young adult life. It looks at how the virus is identified, its risks, transmission, its features , its serology e.t.c
|language || ||english
|wordcount || ||2644 (cca 7.5 pages)
|contextual quality || ||N/A
|language level || ||N/A
|price || ||free
|sources || ||12
Table of contents
1.0 Introduction 1
1.1 Special consideration 1
1.2 IDENTIFICATION OF RUBELLA VIRUS 2
1.3 RISK OF CONGENITALLY AQUIRED INFECTION 2
1.4 RUBELLA REINFECTION DURING PREGNANCY 3
1.5 TRANSMISSION OF RUBELLA VIRUS 3
1.6 PATHOGENESIS OF RUBELLA VIRUS INFECTION 4
1.7 GENOMIC ORGANISATION OF RUBELLA VIRUS 5
1.8 CLASSIFICATION AND ANTIGENIC TYPES 6
1.9 CLINICAL FEATURES OF RUBELLA 6
2.0 PREVENTION OF RUBELLA 8
2.1 DIAGNOSIS OF RUBELLA VIRUS 8
2.2 VIRAL CULTURE OF RUBELLA 9
2.3 SEROLOGY 10
2.4 REFERENCES 11
Preview of the essay: RUBELLA INFECTION
RUBELLA INFECTION 1.0 Introduction Synonyms: German measles, three days measles. German measles is an acute febrile disease of viral cause that is characterized by a rash and posterior and sub occipital adenopathy. The disease occurs mostly in childhood and young adult life. Infection of pregnant women during the first trimester may result in congenital abnormalities of conceptus (Conn and Conn, 1968) 1.1 Special consideration If a fetus is infected with rubella in the womb, this can cause severe defects known as congenital syndrome .The younger the fetus is at the time of infection, the more likely the syndromes is to occur and the more severe the effect are likely to be. Temporary effects of congenital rubella syndrome may include: ➢ Slow growth in the womb ➢ ...
... perform and allows for either screening or diagnosis (if paired acute and convalescent sera are tested). A four –fold rise or greater in HI antibody titer in paired sera is diagnostic of recent infection. The test may be modified to detect rubella –specific IgM antibody indicative of primary infection.
3) Immunofluorescent antibody assay (IFA)
This is a rapid and sensitive assay. Commercial assay for both IgG and IgM are available. Care must be taken with the IgM assay to avoid false positive results due to complexes with the rheumatoid antibody.
(William Atkinson, M.D., M.P.H, 2002)
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